Keene is a town in central Essex County, New York, United States. It includes the hamlets of Keene, Keene Valley, and St. Huberts, with a total population of 1,105 as of the 2010 census.

The town is part of the Adirondack Park, and includes 15 of the 46 High Peaks, including Mount Marcy, New York’s highest mountain, and the rest of the Great Range. It also includes the Ausable Lakes, the source of the Ausable River. Trailheads for many of the High Peaks are located within the town, along with the Johns Brook Lodge of the Adirondack Mountain Club.